If you've recently done theblood analysisor leurine analysissurely you will have come across this value: albumin.
L'albuminis an importantproteinsplasma (found in the blood) produced by the liver. It performs a large number of functions and when its levels exceed a certain threshold, it indicates a physiological problem.
In this article I will explain the most frequent causes ofhigh albuminfound incomplete urinalysisor in blood tests.
The appearance of albumin in the urine is an indication of various conditions of chronic inflammation, nephrotic syndromes e diabetes (microalbuminuria is a characteristic of diabetic nephropathy).
High albumin in the urine
As a rule, very small amounts of are present in the urineproteinslow molecular weight. L'albuminis a high molecular weight protein and its presence inurineindicates severalkidney pathologies.
When the concentrations ofalbumin in the urinethey are only slightly tall, we speak ofmicroalbuminuria: in these cases, aincreased albumin in the urineit can be related to physical exertion, cold and is completely normalpregnant.
L'high albumin in the urineit is a condition known asalbuminuriaas explained in the article dedicated to red blood cells in urine.
In case ofelevated albumin in the urineit is important to contact your doctor or consult anephrologist(kidney specialist) in order to continue with a more accurate diagnosis. High albumin levels could be related to a large number ofkidney diseaseWhich:
- Glomerulopathy (inflammatory or degenerative disease involving the renal glomeruli)
- Eclampsia (if thehigh albumin in pregnancyit could be Eclampsia gravidarum, the most feared complication of gestosis and childbirth)
- Diabetic nephrosis (statistically, this is a complication of diabetes affecting 30-40% of type 1 diabetes sufferers and between 10-20% of type 2 diabetics)
- Multiple myeloma (cancer typical of old age that affects some blood cells)
- Polycystic kidney
Other causes. L'high albumin, often, it can also be justified by febrile states, vescia diseases, prostate diseases, circulatory insufficiency, diabetes, obesity, gout and kidney transplant.
Pathologies that indirectly involve the kidneys can also causehigh albumin in the urine. Let's talk about:
- Venous congestion
- Heart failure
- Hypertensive states
- Ureter infection
Albumin in urine: normal values
In conditions of good health, as anticipated, the presence of proteins is negligible in the urine and albumin is reported as "absent“.
A normal value ofalbumin in the urineit is indicated between 2 and 15 milligrams in 24 hours. Exceeded this value we speak of microalbuminuria(values between 30 and 300 milligrams in 24 hours) and ofalbuminuriaif the levels ofalbumin in the urineexceed 300 mg.
As anticipated, thealbumin in pregnancyit is "normal" if the levels do not exceed what is intense likemicroalbuminuria.
Under any circumstances, in the event ofalbumin in urineit is important to contact your doctor.
Albumin and kidneys
The kidneys play a crucial role inblood filtrationand inelimination of waste substances channeled into the urinary duct. In good health, the albumin found in the blood is filtered by the kidneys and retained.
In case of inflammation, thealbuminit is not retained by the kidneys and is conveyed among the waste substances to be expelled with the urine. Here's how albumin ends up in our pee. That is why if it is presentalbumin in the urinethe cause is due to akidney damagewhich should never be underestimated.
There are somecausesphysiological, i.e. not related to a disease, which tend to raise the levels of albumin in the blood. For example, in the case of considerable physical exertion, when an individual spends most of the time standing or in the case of the common cold (flu) or in pregnancy.
Albumin: albumin in the blood
The normal range of values of the concentration of albumin in the blood varies from 3.5 to 5.0 g / dl. Albumin represents the most abundant protein in plasma, equal to 55-60% of whey proteins.
Blood albumin levels are known as albuminemia. When thealbumin in the bloodis high we speak ofhyperalbuminemia. If, on the other hand, we talk about hypoalbuminemia, we refer to low albumin.
High albumin values in the blood are a rather rare condition and almost always attributable to a state of dehydration.
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